{"id":10293,"date":"2026-01-31T01:41:26","date_gmt":"2026-01-31T01:41:26","guid":{"rendered":"https:\/\/pharmamachinecn.com\/?p=10293"},"modified":"2026-03-12T02:40:36","modified_gmt":"2026-03-12T02:40:36","slug":"understanding-hot-melt-extrusion-formulation","status":"publish","type":"post","link":"https:\/\/pharmamachinecn.com\/tr\/understanding-hot-melt-extrusion-formulation\/","title":{"rendered":"S\u0131cak Eritme Ekstr\u00fczyon Form\u00fclasyonunu Anlamak"},"content":{"rendered":"
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\u00c7al\u0131\u015fma \u015funu g\u00f6steriyor ki 50% t\u00fcm aktif farmas\u00f6tik bile\u015fenler<\/u><\/a>\u00a0(API'ler) suda \u00e7\u00f6z\u00fcn\u00fcrl\u00fck a\u00e7\u0131s\u0131ndan zay\u0131ft\u0131r. Bu durum, biyoyararlan\u0131m\u0131 s\u0131n\u0131rl\u0131 ve terap\u00f6tik etkinli\u011fi azalm\u0131\u015f dozaj formlar\u0131na yol a\u00e7ar. Bu zorluk, ila\u00e7 emilimini art\u0131rmak i\u00e7in yenilik\u00e7i teknolojiye olan ihtiyac\u0131 do\u011furmu\u015ftur.<\/p>

Bu a\u00e7\u0131dan bak\u0131ld\u0131\u011f\u0131nda, s\u0131cak eriyik ekstr\u00fczyon form\u00fclasyonu etkili bir yakla\u015f\u0131m olarak kar\u015f\u0131m\u0131za \u00e7\u0131kmaktad\u0131r. Bu verimli sistemi kullanarak, daha tutarl\u0131 ila\u00e7 kalitesi elde edebilirsiniz. Ana s\u00fcreci kapsaml\u0131 bir \u015fekilde ele alal\u0131m!<\/p>

S\u0131cak Eritme Ekstr\u00fczyon Form\u00fclasyonu Nedir?<\/strong><\/h2>

S\u0131cak eriyik ekstr\u00fczyon form\u00fclasyonu (HME) s\u00fcrekli bir i\u015flemdir.\u00a0ila\u00e7 \u00fcretim s\u00fcreci<\/u><\/a>. Bu teknikte, bir ila\u00e7 ve bir polimer kontroll\u00fc ko\u015fullar alt\u0131nda kar\u0131\u015ft\u0131r\u0131l\u0131r. Geli\u015ftiriciler, homojen bir da\u011f\u0131l\u0131m olu\u015fturmak i\u00e7in hassas bir s\u0131cakl\u0131k ve bas\u0131n\u00e7 ayarlarlar.<\/p>

\"S\u0131cak
S\u0131cak Eritme Ekstr\u00fczyon Form\u00fclasyon Ak\u0131\u015f \u015eemas\u0131.<\/strong><\/em><\/figcaption><\/figure>

Geleneksel y\u00f6ntemlerin aksine, bu teknoloji \u00e7\u00f6z\u00fcc\u00fc ihtiyac\u0131n\u0131 ortadan kald\u0131r\u0131yor. Bu da onu t\u0131bbi preparatlar i\u00e7in daha s\u00fcrd\u00fcr\u00fclebilir bir se\u00e7enek haline getiriyor.\u00a0ResearchGate'in verilerine g\u00f6re, t\u0131p e\u011fitimi (HME) y\u00fcksek \u00f6ncelikli bir aland\u0131r.<\/u><\/a>\u00a0\u00c7\u00f6z\u00fcc\u00fc i\u00e7ermeyen ve \u00e7evre dostu yakla\u015f\u0131m\u0131 nedeniyle.<\/p>

S\u0131cak Eritme Ekstr\u00fczyon Form\u00fclasyonu \u0130\u015flemi<\/strong><\/h2>

Bu i\u015flem, polimerin eritilmesi ve mekanik kuvvet kullan\u0131larak aktif farmas\u00f6tik bile\u015fenin (API) i\u00e7ine kat\u0131lmas\u0131yla ba\u015flar. Daha sonra bu erimi\u015f kar\u0131\u015f\u0131m bir ekstr\u00fcder kal\u0131b\u0131ndan ge\u00e7irilir. Bu, homojen bir \u00fcr\u00fcn olu\u015fmas\u0131na yol a\u00e7ar. So\u011fuduktan sonra, ekstr\u00fcdat istenen dozaj \u015fekline getirilir. Tabletler, peletler veya filmler olabilir. \u0130\u015fte ad\u0131m ad\u0131m bir k\u0131lavuz:<\/p>

1. Besleme<\/strong><\/h3>

\u0130la\u00e7 ve yard\u0131mc\u0131 maddelerin \u00f6nceden kar\u0131\u015ft\u0131r\u0131lm\u0131\u015f kar\u0131\u015f\u0131m\u0131, \u00f6nce bir hazne arac\u0131l\u0131\u011f\u0131yla ekstr\u00fcdere beslenir. Bu ad\u0131m, t\u00fcm bile\u015fenlerin sisteme kontroll\u00fc bir h\u0131zda girmesini sa\u011flar. Do\u011fru besleme, homojen bir bile\u015fimin korunmas\u0131na yard\u0131mc\u0131 olur.<\/p>

2. Is\u0131tma ve Kar\u0131\u015ft\u0131rma<\/strong><\/h3>

Ekstr\u00fcderin i\u00e7inde, kar\u0131\u015f\u0131m kontroll\u00fc \u0131s\u0131tma ve kesme kuvvetlerine maruz kal\u0131r. Polimer erir ve ilac\u0131 homojen bir \u015fekilde da\u011f\u0131t\u0131r. Sonu\u00e7 olarak homojen bir kar\u0131\u015f\u0131m elde edilir.<\/p>

3. Ekstr\u00fczyon<\/strong><\/h3>

Erimi\u015f malzeme daha sonra bir kal\u0131ptan ge\u00e7irilir. Bu i\u015flem, istenen \u015fekil ve boyutlarda bir ekstr\u00fcdat olu\u015fturur.<\/p>

4. So\u011futma ve \u00d6\u011f\u00fctme<\/strong><\/h3>

Ekstr\u00fcdat so\u011futulur ve uygun boyutlara \u00f6\u011f\u00fct\u00fcl\u00fcr. Bu ad\u0131m, daha sonraki i\u015flemlerin yap\u0131lmas\u0131n\u0131 sa\u011flar.\u00a0kat\u0131 dozaj formlar\u0131<\/u><\/a>.<\/p>

HME Prosesinde Kullan\u0131lan Ekipmanlar<\/strong><\/h2>

S\u0131cak eriyik ekstr\u00fczyon form\u00fclasyonunun ba\u015far\u0131s\u0131 b\u00fcy\u00fck \u00f6l\u00e7\u00fcde \u00f6zel ekipman kullan\u0131m\u0131na ba\u011fl\u0131d\u0131r. Ba\u015fl\u0131ca makineler \u015funlard\u0131r:<\/p>

Yemlikler<\/strong><\/h3>

Besleyiciler, kar\u0131\u015f\u0131m\u0131 ekstr\u00fcdere beslemek i\u00e7in kullan\u0131lan hassas cihazlard\u0131r. Malzeme ak\u0131\u015f\u0131n\u0131n istikrarl\u0131 kalmas\u0131n\u0131 sa\u011flamak i\u00e7in besleme h\u0131z\u0131n\u0131 d\u00fczenlerler.<\/p>

\u00c7ift Vidal\u0131 Ekstr\u00fcder (TSE)<\/strong><\/h3>

HME i\u015flemindeki temel bile\u015fen, \u00e7ift vidal\u0131 bir ekstr\u00fcderdir. Bu ekstr\u00fcder, \u0131s\u0131t\u0131lm\u0131\u015f bir namlu i\u00e7inde d\u00f6nen, birbirine kenetlenmi\u015f iki vidadan olu\u015fur.<\/p>

Bu mekanizma, farkl\u0131 s\u0131cakl\u0131k b\u00f6lgeleri arac\u0131l\u0131\u011f\u0131yla verimli bir kar\u0131\u015ft\u0131rma sa\u011flar. Polimer matrisi i\u00e7inde ilac\u0131n homojen bir \u015fekilde da\u011f\u0131lmas\u0131n\u0131 garanti eder.\u00a0Ulusal T\u0131p K\u00fct\u00fcphanesi<\/u><\/a>\u00a0TSE'nin verimli kar\u0131\u015ft\u0131rma ve gran\u00fclasyon sa\u011flad\u0131\u011f\u0131n\u0131 ortaya koyuyor.<\/p>

Is\u0131tma Sistemi<\/strong><\/h3>

Ekstr\u00fcderdeki s\u0131cakl\u0131\u011f\u0131 kontrol etmek i\u00e7in bir \u0131s\u0131tma sistemine ihtiya\u00e7 duyulur. Bu sistem, ilac\u0131n bozulmas\u0131na neden olmadan polimerin homojen bir \u015fekilde erimesini sa\u011flar. B\u00f6ylece, bu d\u00fczenek form\u00fclasyon boyunca optimum i\u015flem ko\u015fullar\u0131n\u0131 korur.<\/p>

Kal\u0131p Montaj\u0131<\/strong><\/h3>

Kal\u0131b\u0131n temel i\u015flevi, \u00fcr\u00fcn\u00fcn \u015fekillerini belirlemektir.\u00a0kal\u0131p tasar\u0131m\u0131n\u0131 ayarlamak<\/u><\/a>, \u00dcreticiler, istedikleri dozaj formunu \u00fcretebilirler. \u00d6rne\u011fin, yuvarlak bir kal\u0131p, yuvarlak bir tablet \u00fcretmek i\u00e7in kullan\u0131l\u0131r.<\/p>

So\u011futma Konvey\u00f6r\u00fc<\/strong><\/h3>

Kal\u0131p montaj\u0131ndan sonra, ekstr\u00fczyon \u00fcr\u00fcn\u00fc genellikle s\u0131cakt\u0131r. \u00dcr\u00fcn\u00fc kat\u0131la\u015ft\u0131rmak i\u00e7in so\u011futma konvey\u00f6r\u00fc etkilidir. Uygun so\u011futma, \u00fcr\u00fcn\u00fcn yap\u0131s\u0131n\u0131 korur ve deformasyonu \u00f6nler.<\/p>

Peletleyici veya Kesici<\/strong><\/h3>

Peletleme makinesi, so\u011futulmu\u015f ekstr\u00fcdat\u0131 homojen pelet veya gran\u00fcller halinde kesmek i\u00e7in kullan\u0131l\u0131r. Bunlar daha sonra tablet veya kaps\u00fcl haline getirilir.<\/p>

A\u015fa\u011f\u0131 Ak\u0131\u015f \u0130\u015fleme Ekipmanlar\u0131<\/strong><\/h3>

Son i\u015flem a\u015famas\u0131ndaki ekipmanlar aras\u0131nda kar\u0131\u015ft\u0131r\u0131c\u0131lar, tablet presleri ve kaplama makineleri bulunur. Bunlar, nihai ila\u00e7 \u00fcr\u00fcn\u00fcn\u00fcn kalitesini art\u0131rmak i\u00e7in kullan\u0131l\u0131r.<\/p>

Te\u00e7hizat<\/strong><\/td>Tan\u0131m<\/strong><\/td>\u0130\u015flev<\/strong><\/td><\/tr>
Yemlikler<\/td>Kar\u0131\u015f\u0131m\u0131 ekstr\u00fcdere iletir.<\/td>Homojen bir bile\u015fim i\u00e7in s\u00fcrekli bir ak\u0131\u015f d\u00fczenleyin.<\/td><\/tr>
\u00c7ift Vidal\u0131 Ekstr\u00fcder<\/td>\u0130ki d\u00f6ner vidal\u0131 ana \u00fcnite<\/td>Malzemeleri kar\u0131\u015ft\u0131r\u0131r, eritir ve e\u015fit \u015fekilde da\u011f\u0131t\u0131r.<\/td><\/tr>
Is\u0131tma Sistemi<\/td>Ekstr\u00fcder namlusu boyunca \u0131s\u0131y\u0131 d\u00fczenleyin.<\/td>\u0130lac\u0131n yap\u0131s\u0131n\u0131 bozmadan polimerlerin erimesine yard\u0131mc\u0131 olur.<\/td><\/tr>
Kal\u0131p Montaj\u0131<\/td>Ekstr\u00fcderin ucundaki \u015fekillendirme aleti<\/td>Erimi\u015f kar\u0131\u015f\u0131m\u0131 istenilen \u015fekle d\u00f6n\u00fc\u015ft\u00fcr\u00fcn.<\/td><\/tr>
So\u011futma Konvey\u00f6r\u00fc<\/td>Ekstr\u00fczyon i\u015fleminden sonra kullan\u0131lan bir sistem.<\/td>Ekstr\u00fczyon \u00fcr\u00fcn\u00fc so\u011futur ve kat\u0131la\u015ft\u0131rarak \u015feklini korumas\u0131n\u0131 sa\u011flar.<\/td><\/tr>
Peletleyici \/ Kesici<\/td>So\u011fuduktan sonra mekanik kesici kullan\u0131ld\u0131.<\/td>Ekstr\u00fcdat\u0131 homojen peletler veya gran\u00fcller halinde kesin.<\/td><\/tr>
A\u015fa\u011f\u0131 Ak\u0131\u015f Ekipmanlar\u0131<\/td>Kar\u0131\u015ft\u0131r\u0131c\u0131lar, tablet presleri ve kaplama makineleri dahildir.<\/td>Peletleri nihai dozaj formlar\u0131na d\u00f6n\u00fc\u015ft\u00fcr\u00fcr.<\/td><\/tr><\/tbody><\/table><\/div>

S\u0131cak Eritme Ekstr\u00fczyon Form\u00fclasyonunun Uygulamalar\u0131<\/strong><\/h2>

HME teknolojisinin ila\u00e7 sekt\u00f6r\u00fcnde \u00e7ok geni\u015f uygulama alanlar\u0131 bulunmaktad\u0131r. \u0130\u015fte genel bir bak\u0131\u015f:<\/p>

Kat\u0131 Da\u011f\u0131l\u0131mlar:<\/strong><\/h3>

S\u0131cak eriyik ekstr\u00fczyon form\u00fclasyonunun en yayg\u0131n kullan\u0131m alanlar\u0131ndan biri kat\u0131 dispersiyonlar\u0131n geli\u015ftirilmesidir. Bu teknoloji, d\u00fc\u015f\u00fck \u00e7\u00f6z\u00fcn\u00fcrl\u00fc\u011fe sahip ila\u00e7lar\u0131n amorf bir forma d\u00f6n\u00fc\u015ft\u00fcr\u00fclmesine yard\u0131mc\u0131 olur. \u00c7\u00f6z\u00fcnme h\u0131z\u0131n\u0131 art\u0131rarak ilac\u0131n v\u00fccutta daha etkili olmas\u0131n\u0131 sa\u011flar.<\/p>

Kontroll\u00fc ve S\u00fcrekli Sal\u0131m Sistemleri<\/strong><\/h3>

Bu i\u015flem, ila\u00e7 sal\u0131n\u0131m h\u0131zlar\u0131 \u00fczerinde hassas kontrol sa\u011flar. S\u0131k dozlama ihtiyac\u0131n\u0131 azalt\u0131r ve tedavi edici etkiyi art\u0131r\u0131r.<\/p>

Tat Maskeleme<\/strong><\/h3>

S\u0131cak eriyik ekstr\u00fczyon form\u00fclasyonu, baz\u0131 ila\u00e7lar\u0131n ho\u015f olmayan tad\u0131n\u0131 maskelemek i\u00e7in de kullan\u0131\u015fl\u0131d\u0131r.\u00a0API'yi yerle\u015ftirme<\/u><\/a>\u00a0Polimer matris i\u00e7inde, ac\u0131 tat etkili bir \u015fekilde engellenir.<\/p>

\u00c7\u00f6z\u00fcc\u00fc \u0130\u00e7ermeyen \u0130\u015fleme Uygulamalar\u0131<\/strong><\/h3>

HME teknolojisi, \u00e7\u00f6z\u00fcc\u00fclere olan ihtiyac\u0131 ortadan kald\u0131r\u0131r. \u00d6zellikle neme ve \u00e7\u00f6z\u00fcc\u00fclere kar\u015f\u0131 hassas veya karars\u0131z ila\u00e7lar i\u00e7in son derece uygundur. Bu \u00f6zelli\u011fi, geleneksel tekniklere k\u0131yasla daha g\u00fcvenli bir yakla\u015f\u0131m olmas\u0131n\u0131 sa\u011flar.<\/p>

SSS<\/strong><\/h2>

S\u0131cak Eritme Ekstr\u00fczyon Form\u00fclasyonu \u0130\u00e7in Hangi \u0130la\u00e7 T\u00fcrleri Uygundur?<\/strong><\/h3>

Bu teknik, \u00e7\u00f6z\u00fcn\u00fcrl\u00fc\u011f\u00fc d\u00fc\u015f\u00fck ila\u00e7lar i\u00e7in idealdir. Ayr\u0131ca, \u0131s\u0131ya duyarl\u0131 form\u00fclasyonlar da HME y\u00f6ntemiyle i\u015flenebilir.<\/p>

S\u0131cak Eritme Ekstr\u00fczyonu Solvent \u0130\u00e7ermeyen Bir \u0130\u015flem midir?<\/strong><\/h3>

Evet. HME, \u00e7\u00f6z\u00fcc\u00fclere olan ihtiyac\u0131 ortadan kald\u0131r\u0131r. Bu da onu neme duyarl\u0131 ila\u00e7lar i\u00e7in uygun hale getirir.<\/p>

S\u0131cak Eritme Ekstr\u00fczyon Teknolojisinin Gelece\u011fi Nedir?<\/strong><\/h3>

Gelecek son derece umut verici. S\u00fcrekli \u00fcretimle entegrasyon, kaliteli ila\u00e7 \u00fcretimi potansiyelini geni\u015fletiyor.<\/p>

\u00c7\u00f6z\u00fcm<\/strong><\/h2>

S\u0131cak eriyik ekstr\u00fczyon form\u00fclasyonu, ila\u00e7 \u00fcretiminde d\u00f6n\u00fc\u015ft\u00fcr\u00fcc\u00fc bir yakla\u015f\u0131md\u0131r. Daha etkili bir ila\u00e7 da\u011f\u0131t\u0131m sistemi sunar. Bununla birlikte, \u00fcr\u00fcn\u00fcn kalitesi kullan\u0131lan ekipmana ba\u011fl\u0131d\u0131r. G\u00fcvenilir dozaj formlar\u0131 \u00fcretmek i\u00e7in \u015funlar\u0131 g\u00f6z \u00f6n\u00fcnde bulundurun: Finetech Pharma makineleri.<\/u><\/a>\u00a0\u0130htiya\u00e7lar\u0131n\u0131z\u0131 kar\u015f\u0131layacak geni\u015f bir t\u0131bbi ekipman yelpazesi sunuyoruz. Bu nedenle, ila\u00e7 \u00fcretimini kolayla\u015ft\u0131rmak i\u00e7in en kaliteli \u00fcr\u00fcnlerimizden yararlan\u0131n!<\/p>

Referanslar:<\/strong><\/h2>

\u0130la\u00e7 end\u00fcstrisinde s\u0131cak eriyik ekstr\u00fczyonu<\/strong><\/em><\/span><\/a><\/p>

S\u0131cak eriyik ekstr\u00fczyon, transdermal form\u00fclasyon i\u00e7in siklodekstrin bazl\u0131 poli(ps\u00f6do)rotaxanlar\u0131n \u00f6zelliklerini geli\u015ftirir<\/strong><\/em><\/span><\/a>.<\/p>

S\u0131cak Eriyik Ekstr\u00fczyon Form\u00fclasyonu ve \u00dcretimi<\/strong><\/em><\/span><\/a>.<\/p>

Polivinil Alkol ile S\u0131cak Eriyik Ekstr\u00fczyon Form\u00fclasyonu Kullan\u0131larak API \u00c7\u00f6z\u00fcn\u00fcrl\u00fc\u011f\u00fcn\u00fcn \u0130yile\u015ftirilmesi<\/strong><\/em><\/span><\/a>.<\/p>

Telif Hakk\u0131 Uyar\u0131s\u0131:\u00a0<\/b><\/h2>

Finetech Group'un \u00f6nceden a\u00e7\u0131k yaz\u0131l\u0131 onay\u0131 olmadan bu web sitesindeki herhangi bir i\u00e7eri\u011fi \u00e7o\u011faltamaz, de\u011fi\u015ftiremez, yay\u0131nlayamaz, g\u00f6r\u00fcnt\u00fcleyemez, iletemez veya herhangi bir \u015fekilde istismar edemezsiniz veya bu t\u00fcr i\u00e7eri\u011fi herhangi bir veritaban\u0131 olu\u015fturmak i\u00e7in kullanamazs\u0131n\u0131z. \u0130\u00e7eri\u011fi kullanma izni i\u00e7in l\u00fctfen ileti\u015fime ge\u00e7in: info@pharmamachinecn.com<\/span><\/a><\/p>

Yasal Uyar\u0131:<\/b><\/h2>

Bu makalede yer alan bilgiler yaln\u0131zca genel bilgilendirme ama\u00e7l\u0131d\u0131r. \u015eirket, herhangi bir bilginin do\u011frulu\u011funu, g\u00fcncelli\u011fini veya eksiksizli\u011fini garanti etmez ve \u015eirket, bu makalenin i\u00e7eri\u011findeki hatalar veya eksiklikler i\u00e7in hi\u00e7bir sorumluluk kabul etmez.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Study shows that 50% of all active pharmaceutical ingredients\u00a0(APIs) exhibit poor water solubility. It leads to dosage forms with limited […]<\/p>\n","protected":false},"author":1,"featured_media":10385,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[67],"tags":[],"class_list":["post-10293","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pills"],"acf":[],"_links":{"self":[{"href":"https:\/\/pharmamachinecn.com\/tr\/wp-json\/wp\/v2\/posts\/10293","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmamachinecn.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmamachinecn.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmamachinecn.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmamachinecn.com\/tr\/wp-json\/wp\/v2\/comments?post=10293"}],"version-history":[{"count":20,"href":"https:\/\/pharmamachinecn.com\/tr\/wp-json\/wp\/v2\/posts\/10293\/revisions"}],"predecessor-version":[{"id":13281,"href":"https:\/\/pharmamachinecn.com\/tr\/wp-json\/wp\/v2\/posts\/10293\/revisions\/13281"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmamachinecn.com\/tr\/wp-json\/wp\/v2\/media\/10385"}],"wp:attachment":[{"href":"https:\/\/pharmamachinecn.com\/tr\/wp-json\/wp\/v2\/media?parent=10293"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmamachinecn.com\/tr\/wp-json\/wp\/v2\/categories?post=10293"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmamachinecn.com\/tr\/wp-json\/wp\/v2\/tags?post=10293"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}